A condition in which no semen is expelled from the penis during sexual arousal

A relatively uncommon disorder, anejaculation — or the absence of any semen — can occur as a result of spinal cord injury, previous surgery, diabetes, or multiple sclerosis. It may also be caused by abnormalities present at birth as well as other mental, emotional or unknown problems. Medical therapy with drugs is usually the first line of treatment, but if that fails, the next step is either rectal probe electroejaculation (RPE) or penile vibratory stimulation (PVS). PVS consists of rhythmic vibratory stimulation of the tip and shaft of the penis to encourage a natural climax. While relatively non-invasive, it is less successful than RPE, particularly in severe cases. RPE, except in the spinal cord injured patient, is usually performed under anesthesia and retrieves sperm in 90 percent of patients. While cell density with this procedure is excellent, sperm movement and shape are still limiting fertility factors. Assisted reproductive techniques, such as in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI), have become increasingly important to patients with anejaculation.

the inability to ejaculate.