Definitions for "Antigen-presenting cell"
Related Terms:
Antigen presenting cell, Cytotoxic t cell, Antigen presentation, Helper cell, Cell-mediated immunity, Suppressor t cells, Cellular immunity, Cell mediated immunity, Antibody-dependent cell-mediated cytotoxicity, Cd4, Major histocompatibility complex, T lymphocyte, Helper t cell, Antigen processing, Helper t cells, Mhc, Opsonization, Cytokines, Ctl, Cytotoxic t lymphocyte, Memory cell, Complement, T-cell receptor, Interferons, Humoral immunity, Interleukin-1, Monoclonal antibodies, Memory cells, Cytokine, Interleukins, Immune system, Cytotoxic t cells, T4 cell, Interleukin, Complement system, Antibodies, Helper t-cell, Killer t cell, Antibody, Nk cells, Dendritic cells, Monoclonal antibody, Antibody-mediated immunity, Interferon, Cellular immune response, Natural killer cells, T cell receptor, Natural killer cell, Interleukin-2, Lymphokine
Antigen-processing cells ingest antigen and chop it into small fragments that are then packaged within the major histocompatibility complex molecules and shuttled to the surface of the cell membrane for presentation. Professional antigen presenting cells are dendritic cells, macrophages, and B cells.
a cell (e.g., dendritic cell, macrophage) that processes antigen proteins and displays short peptide fragments on its surface for recognition by T-cells.
A cell that can process an infectious agent and present pieces of it (antigens) to T-cells. Dendritic cells and macrophages function as APCs.
A type of cell that provokes an immune response from T-cells by binding foreign antigens to its own surface and then interacting with the T-cells. Also known as antigen-processing cell
The cell type that collects foreign material (see antigen) and digests it into pieces that can be recognized by the immune system. The APC presents the antigen to the helper T cells, the CD4+ T cells; this results in the initiation of expansion of an immune response targeted against the foreign material. APCs are B cells, macrophages, or dendritic cells (see entries for these terms).
A specialized type of white blood cell that engulfs antigens and breaks them down into smaller fragments. These fragments are transported to the surface of the APC, where they are linked to special marker proteins and "presented" to a T cell. This process results in instructing the T cell to recognize that substance or component.
A cell involved in the immune process
A cell that displays peptide fragments of protein antigens, in association with MHC molecules, on its surface and activates antigen-specific T cells. In addition to displaying peptide-MHC complexes, APCs must also express costimulatory molecules to activate T lymphocytes optimally (1).
A cell that ingests and processes foreign substance (e.g. from invading viruses or bacteria) and displays the resulting antigen fragments (small peptides) on its surface to activate those T cells that respond specifically to that antigen.
APC. A cell that shows antigen on its surface to other cells (T Cells) of the immune system. This is an important part of an immune response.
a cell (e.g., macrophage) that processes antigen proteins and displays the short peptide fragments on its surface in conjunction with major histocompatibility (MHC) proteins, enabling recognition by T-cells.
(ANN-teh-jin pre-ZENT-ing sell) Cell that shows antigen on its surface to other cells of the immune system, which is an important part of an immune response. Different types of APCs include macrophages, endothelial cells, dendritic cells and Langerhans cells of the skin.
B cell, macrophage, dendritic cell or other cell that ingests and processes foreign bodies such as viruses and displays the resulting antigen fragments on its surface to attract and activate the CD4+ T cells that respond specifically to that antigen. (See also dendritic cell; macrophage.)
A specialized cell which functions as the starting engine of the immune system by processing antigens and presenting them to the immune system. The result is a specific immune response consisting of either or both a cellular response and antibody response.
A specialized type of cell, bearing cell surface class II MHC (major histocompatibility complex) molecules, involved in processing and presentation of antigen to inducer, or helper , T cells. Examples: macrophage, dendritic cells.
a cell that displays an antigen with an MHC molecule on the cell surface.
white blood cells that encounter an invading organism, digest it, and present an antigen on their cell surface
A cell that processes antigens and displays them, bound to MHC proteins; essential to the initiation of a normal immune response.
Cell that presents antigen, complexed with MHC proteins on its surface, to T cells.
An antigen-presenting cell (APC) is a cell that displays foreign antigen complexed with MHC on its surface. T-cells may recognize this complex using their T-cell receptor (TCR). Although almost every cell in the body is technically an APC, since it can present antigen to CD8+ T cells via MHC class I molecules, the term is often limited to those specialized cells that can prime T cells (i.e., activate a T cell that has not been exposed to antigen, termed a naive T cell).