Definitions for "Bisphosphonates"
A class of chemical compounds that are potent inhibitors of osteoclast-mediated bone resorption.
class of medications designed to inhibit the breakdown of bone tissue by decreasing the activity of osteoclasts. The class includes Fosamax, Zometa, and Aredia.
synthetic analogs of endogenously-produced pyrophosphate that bind to hydroxyapatite in the bone matrix and regulate osteoclast activity; some are used to suppress skeletal cancer metastases.