The Cochrane Collaboration is an international effort by researchers, practitioners and consumers to sift through research on the effects of health care. The Collaboration prepares, maintains and disseminates systematic reviews of the effects of health care. The Collaboration prepares, maintains and disseminates systematic reviews of the effects of health care. The reviews are published in the Cochrane Database of Systematic Reviews - one of the components of a regular, electronic publication called The Cochrane Library.