is a rare prion disorder that can occur sporadically, as a consequence of using infected graft material (eg dural graft - latrogenic CJD) and probably through BSE infected meat (causing new variant CJD). In all cases patients present with a rapidly progressive neurological disorder with dementia, ataxia and myoclonus.
CJD. A fatal, human brain illness with genetic or unknown causes, appears in one person in a million per year.
nbspa rare and fatal neurodegenerative disease of unknown cause. Symptoms are progressive dementia, dysarthria (difficult or defective speech), muscle wasting, and various involuntary movements. Although CJD appears to occur as a predominantly sporadic disorder it can also occur as a dominantly inherited or infective condition.
An type of spongiform encephalopathy. The brain develops numerous tiny holes. Symptoms include personality changes, hallucinations, muscle twitching and muscle stiffness, gait changes, poor coordination, trouble speaking, drowsiness, dementia, memory loss, and anxiety.
A disease in which rapid progressive degeneration of brain tissue results in dementia and eventually death
Chronic, progressive, fatal disease of the central nervous system caused by a prion.
The Condition"...The only way to confirm a diagnosis of CJD is by brain biopsy or autopsy..."
The Condition"...to other people from grafts of dura mater (a tissue that covers the brain), transplanted corneas, implantation of inadequately sterilized electrodes in the brain, and injections of contaminated pituitary growth hormone derived from human pituitary glands taken from cadavers..."
rare (usually fatal) brain disease (usually in middle age) caused by an unidentified slow virus; characterized by progressive dementia and gradual loss of muscle control
a rare, degenerative, fatal brain disorder believed to be linked to an abnormal form of a protein called a prion.
Fatal, human TSE, strikes one person in a million.
a degenerative neurological disorder of humans thought to be transmitted by abnormal isoforms of neural proteins called prions. CJD is one of a group of related diseases known as transmissible spongiform encephalopathies (TSEs).
A disease of humans hypothesized to be caused by a prion, or a small protein, which alters the structure of a normal brain protein, resulting in destruction of brain neural tissue. The most common form is thought to have genetic origins. There is strong epidemiologic and laboratory evidence for a causal association between new variant CJD and BSE.
The Condition"...The disease is transmitted by exposure to brain or nervous system tissue, usually through certain medical procedures..."
an extremely rare disease causing brain damage and death. It is not thought to be transmitted by blood or blood-derived products; however, this is an area of active research.
A human prion-related disease causing serious neurological damage. Classic CJD and new variant CJD (vCJD) are separate conditions. However, both diseases are rapidly progressive and always fatal. It is conceivable that CJD could be transmitted through blood or blood products.
Brain disorder commonly known as "mad cow" disease in Britain.
CJD) A form of degenerative dementia that is inevitably fatal, usually within a year. It can be inherited or caught virally, or it can occur for no known reason. There is some correlation thought to be between the virus and Mad Cow Disease. They are both considered prion diseases—diseases communicated through infectious proteins.
An infectious neurological disease that is a very rare form of encephalopathy thought to be caused by a virus called a prions. The disease occurs primarily in adults, with peak incidence in the late 50s.
A rare case of loss of memory and change in attitude.
A rare disorder of infectious and genetic origin that typically causes memory failure and behavioral changes.
A central nervous system disease that causes presenile dementia, myoclonus, and distinctive electroencephalographic changes. The causative organism is assumed to be a prion.
The Condition"...Opiate drugs can help relieve pain if it occurs, and the drugs clonazepam and sodium valproate may help relieve myoclonus..."
The Condition"...They often develop involuntary muscle jerks called myoclonus, and they may go blind or lose bladder control..."
(kroits ' felt - yä ' kôp) A disease (also known as "Classic CJD") that creates a protein plaque on the brain and eventually leads to a rapid death. It usually occurs in patients over the age of 60.
The Condition"... Magnetic resonance imaging (MRI) brain scans also can reveal characteristic patterns of brain degeneration that can help diagnose CJD..."
The Condition"...Standard diagnostic tests will include a spinal tap to rule out more common causes of dementia and an electroencephalogram (EEG) to record the brain's electrical pattern, which can be particularly valuable because it shows a specific type of..."
Creutzfeldt-Jakob disease (CJD) is a very rare and incurable degenerative neurological disorder (brain disease) that is ultimately fatal. It is the most common of the transmissible spongiform encephalopathies (TSEs).