a blood product produced by the Animal Blood Bank. Cryoprecipitate is rich in factor VIII and von Willebrand's factor, so it is used for the treatment of hemophilia A and von Willebrand's disease; it can also be used as a topical hemostatic in surgery.
Component of blood obtained by freezing and thawing plasma. Useful in replacing some clotting factors in patients missing them congenitally or because of operation or trauma.
A blood component made from plasma, containing VWF and factor VIII, commonly used to treat VWD in the past. However, because there is no method to kill viruses in cryoprecipitate, it is no longer recommended.
A form of Factor VIII-concentrated plasma that was first discovered by Dr. Judith Graham Poole in 1965. While a breakthrough in treatment at that time, it is no longer used as the current standard of treatment in the United States.
a concentrated form of Factor VIII used to treat hemophiliacs. The component is produced by thawing fresh frozen plasma for two hours in a 4/C water bath until it yields precipitate of the antihemophilic factor. The plasma unit is then spun in a refrigerated centrifuge to separate the cryoprecipitate from the rest of the plasma.
Cryoprecipitate is a blood product prepared from plasma. Each 15 mL unit contains about 100 U of factor VIII, 350 mg of fibrinogen, von Willebrand factor, factor XIII, and fibronectin.
