injection of a gene that codes for a specific antigen, enabling the recipient to produce that antigen directly to achieve the desired immune response.
A DNA construct that is introduced into cells and subsequently translated into immunogenic proteins.
An experimental vaccine technology in which one or more genes coding for specific antigen(s) are directly injected into the body, where they hopefully produce antigen(s) in the recipient and trigger immune responses. The technology is highly promising for producing simple, inexpensive and heat-stable vaccines.
A nucleic acid vaccine: Genes coding for specific antigenic proteins are injected to produce those antigens and trigger an immune response.
a method for delivering antigens to the immune system by introducing the genetic information (manufacturing instruction) rather than the protein (manufactured product). The DNA vaccine directs the expression of the protein by cells of the immunised organism.
a vaccine that uses genes made of HIV desoxynucleic acid (DNA) to trigger an immune response. In HVTN trials, vaccines using this method use only SOME genes of HIV, not the whole virus. Receiving a vaccine in an HVTN trial cannot infect a participant with HIV or AIDS.
direct injection of a gene(s) coding for a specific antigenic protein(s), resulting in direct production of such antigen(s) within the vaccine recipient in order to trigger an appropriate immune response.
Gene is introduced in an expression vector that allows transcription and translation into the protein
Enables a broad range of applications, including the induction of protective immunity against viral, bacterial, and parasitic infections, and open up new perspectives for the treatment of cancer. Furthermore, based on their Th1-promoting properties, DNA vaccines also balance Th2-mediated immune reactions, which renders them a promising alternative for immunotherapy against allergy. Source: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15119049&dopt=Abstract
