Data Safety Monitoring Board. A board set up by a clinical trial sponsor to evaluate trial progress, safety data, and significant outcomes according to FDA regulations. This committee, comprising community representatives and clinical research experts, may also recommend revisions or discontinuation of a clinical trial if the trial objectives remain unmet or safety concerns arise.
Data Safety Monitoring Board. a group of independent researchers who review the data while the trial is going on, to determine if one drug or drug dose is markedly safer or more effective than another
(Data and Safety Monitoring Board) A committee of independent clinical research experts who review data while a clinical efficacy trial is in progress to ensure that participants are not exposed to undue risk. Also monitors the trial for differences in infection rates between those receiving the vaccine and those receiving placebos.
a group of experts who are not connected to the people doing the research or the companies that make the study drugs
an independent group of experts that advises DMID and the study investigators
data safety monitoring board. an independent group that reviews data during the study and can recommend a study to be stopped if it appears the volunteers are being placed at risk.
see Data and Safety Monitoring Board.
Drug Safety Monitoring Board
See Data Safety and Monitoring Board.
a committee of independent clinical research experts who review data while a clinical trial is in progress. The DSMB ensures that participants are not exposed to undue risk and looks for any differences in effectiveness between the experimental and control groups. The DSMB may review the data in such a way that they know which group received the vaccine and which group did not. This group may also recommend that a trial be modified or stopped if there are safety concerns or if the trial objectives have been achieved. EBV (Epstein-Barr Virus) cell line: a herpesvirus; in vaccine research, used to make target cells for CTL assays.