A protein which lies under the membrane of the muscle fibre and is part of the internal cell skeleton which allows the cell to function normally. the protein that is lacking in DMD.
the protein that's missing in boys with Duchenne muscular dystrophy. Normal muscle cells produce a lot of this. Dystrophin is related to other proteins which are affected in other types of muscular dystrophy.
A rod shaped protein found in muscle cells that connects to the internal structures of muscle cells and helps them to perform movements.
large protein of sarcolemma. Duchenne muscular dystrophy (DMD) is a disease resulting from a deficiency in the dystrophin gene.
The protein missing in individuals with Duchenne muscular dystrophy and reduced in those with Becker muscular dystrophy. search for Dystrophin
a protein found in normal muscle tissue.
a protein, a chemical substance made by muscle fibers.
Large protein found on the inner side of the membrane surrounding each muscle fiber. Its purpose seems to be to maintain shape and structure of the muscle fiber similar to the way joists, rafters and posts keep a house standing. Mutations in the DMD gene result in dystrophin deficiency which constitutes the pathogenic basis of DMD. Back to Homepage
The protein, which is missing in boys with Duchenne muscular dystrophy and reduced in boys with Becker muscular dystrophy. Dystrophin binds to other proteins in the dystrophin-glycoprotein complex (DGC), absence of these components are implicated in different forms of muscular dystrophy.
The product of the Duchenne muscular dystrophy gene.
Dystrophin is a rod-shaped protein, and a vital part of a protein complex which connects the cytoskeleton of a muscle fiber to the surrounding extracellular matrix through the cell membrane.