A drug extracted from a mould growing on rye which has been a mainstay of headache treatment for many years.
                                                            
                                                     
                        
                                                
                        
                        
                            an alkaloid derived from ergot that is less toxic than ergot; causes constriction of blood vessels and is used to treat migraine 
                                                            
                                                     
                        
                                                
                        
                        
                            A drug originally derived from the ergot fungus that constricts blood vessels and has been used since the 1920's to treat migraine headaches.