Bleeding into the skin and other organs due to a deficiency of platelets.
purpura associated with a reduction in circulating blood platelets which can result from a variety of factors
A rare autoimmune disorder characterized by an acute shortage of platelets (cell fragments responsible for blood clotting), which results in bruising and spontaneous bleeding. The platelet count becomes very low and spontaneous bleeding from the gums, gastrointestinal tract and nose can occur. Physical examination may show enlargement of the spleen. A rash typically occurs due to microscopic bleeding of small blood vessels in the skin. Platelet counts under 10,000 can lead to spontaneous bleeding into the brain causing death. Treatment with corticosteroids (steroid medications) is generally effective. Surgical removal of the spleen (splenectomy) is indicated in some cases. Antibodies against platelets can be demonstrated particularly in the chronic form of the disease, which is predominantly affecting female adults.
A disorder that causes the immune system to make antibodies that destroy platelets, a type of blood cell. When the platelets are destroyed, a person is more susceptible to easy bruising and bleeding.
An autoimmune disease where the body makes antibodies against its own platelets.
Idiopathic thrombocytopenic purpura (ITP) (id-ee-o-PATH-ic throm-bo-cy-to-PE-nic pur-PUR-a) is a bleeding disorder in which the blood does not clot as it should. This is due to too few platelets. A symptom of ITP is frequent bruising of the skin. For more information on ITP from the National Heart, Lung, and Blood Institute, click here.
Also known as immune thrombocytopenic purpura. ITP is classified as an autoimmune disease. It is a rare disorder characterized by an acute shortage of platelets with resultant bruising and spontaneous bleeding. Anti-platelet antibodies are detectable in some cases. It may be present in either an acute or a chronic form.
a blood disorder characterized by an abnormal decrease in the number of blood platelets, which results in internal bleeding. There are two forms of idiopathic thrombocytopenic purpura: acute thrombocytopenic purpura and chronic thrombocytopenic purpura.
Idiopathic thrombocytopenic purpura (ITP) is the condition of having a low platelet count (thrombocytopenia) of no known cause (idiopathic). As most causes appear to be related to antibodies against platelets, it is also known as immune thrombocytopenic purpura. Although most cases are asymptomatic, very low platelet counts can lead to a bleeding diathesis and purpura.