Definitions for "Idiopathic thrombocytopenic purpura"
Bleeding into the skin and other organs due to a deficiency of platelets.
purpura associated with a reduction in circulating blood platelets which can result from a variety of factors
A rare autoimmune disorder characterized by an acute shortage of platelets (cell fragments responsible for blood clotting), which results in bruising and spontaneous bleeding. The platelet count becomes very low and spontaneous bleeding from the gums, gastrointestinal tract and nose can occur. Physical examination may show enlargement of the spleen. A rash typically occurs due to microscopic bleeding of small blood vessels in the skin. Platelet counts under 10,000 can lead to spontaneous bleeding into the brain causing death. Treatment with corticosteroids (steroid medications) is generally effective. Surgical removal of the spleen (splenectomy) is indicated in some cases. Antibodies against platelets can be demonstrated particularly in the chronic form of the disease, which is predominantly affecting female adults.
(This is considered an AIDS-defining condition in the United States.)