Antibody variants localized to the variable portion of an immunoglobulin that are recognised by their antigenic determinants. The determinants are composed from the antigen-combining site or CDRs. Every unique antigenic determinant has a specific antibody with its own unique idiotype.
Property of an antibody molecule that is unique to that antibody.
The patient-specific "fingerprint", or unique protein on the patient's tumor, that is identified and used to manufacture a patient-specific vaccine.
The antigenic characteristic of the V region of an antibody.
the unique part of the variable region of an antibody. The idiotype can in turn act as an antigen for other antibodies (anti-idiotypes).
An antigenic determinant within the binding site of an antibody that is recognized by another antibody.
the unique appearence of an antibody binding site to the immune system
a patient-unique "fingerprint" portion of an antibody present on the surface of B cells
The combined antigenic determinants (idiotopes) found on antibodies of an individual that are directed at a particular antigen; such antigenic determinants are found only in the variable region.