See immunoreceptor tyrosine-based activation motif.

An immunoreceptor tyrosine-based activation motif (ITAM) consists of two tyrosine residues separated by between nine and 12 amino acid residues. In the classic ITAM sequence, either a leucine residue or an isoleucine residue occupies the fourth spot. ITAMs were initially identified in the cytoplasmic tails of CD3 molecules (Janeway et al., 2005).

Integrated Training Area Management (program)