decreased erythrocyte production due to a deficiency of either vitamin B12 or folic acid. The abnormal and delayed cell division in the bone marrow results in formation of a population of unusually large precursor cells called megaloblasts.
See Anemia, megaloblastic.
a type of anemia in which a lack of the vitamin B12 or folic acid interferes with red blood cells and causes them to be enlarged and deformed, resulting in tiredness and weight loss
a rare blood disorder in which the body does not absorb enough vitamin B12 from the digestive tract, resulting in an inadequate amount of red blood cells produced.
anemia characterized by many large immature and dysfunctional red blood cells (megaloblasts) in the bone marrow; associated with pernicious anemia
Anemia characterized by the presence of megaloblasts (large red cells and homogeneous cytoplasm with large nucleus and granular chromatin) in the bone marrow.
a rare blood disorder in which there is a deficiency of either folate (a B vitamin) or Vitamin B-12, resulting in an inadequate amount of red blood cells produced.
Low red blood cell count, characterized by the presence in the blood of large, immature, nucleated cells (megaloblasts) that are forerunners of red blood cells. Red blood cells, when mature, have no nucleus.
Megaloblastic anemia is anemia resulting from a deficiency of vitamin B12 and folic acid.
