proteins made by cells which all belong to the same clone are identical and are called monoclonal.
A clone of cells derived from a single cell. The term is used to differentiate those antibodies derived from a single cell (monoclonal antibody) from those derived from multiple cells (polyclonal antibody). Monoclonal antibodies are produced by cell hybridization techniques. (See Polyclonal) mRNA: Messenger ribonucleic acid
A group of cells that are all identical copies of an original cell.
An antibody produced by culturing a single type of cell. It therefore consists of a single species of immunoglobulin molecules.
of antibodies - derived from a single antibody-producing cell, and therefore having highly consistent properties
Pertaining to a protein from a single clone of cells, all molecules of which are the same; e.g., in the case of Bence Jones protein, the chains are all kappa or lambda.
All the same, as when gamma globulin cells made by plasma cells have proliferated from a single cell. Such a population of identical cells is called a "clone," and "monoclonal" means a single clone.
treatment that uses a manufactured antibody to antibody therapy fight disease
From a population of cells which is derived from one cell (a clone).
Pertaining to a single clone of cells, a single cell and the progeny of that cell. As opposed to polyclonal. See the entire definition of Monoclonal
formed from a single group of identical cells
A single, malignant plasma cell.
arising from a single cell, as in antibodies specific for a particular antigen and derived from hybridoma cells.
Derived from a single cell; pertaining to a single clone.
The cells that are derived from a single common ancestor cell are part of a single clone. For example, all leukemias, lymphomas, and myeloma are the result of the malignant transformation of a single cell and are monoclonal diseases. If those cells are immunoglobulin-producing cells (B lymphocytes or their derivative plasma cells), the immunoglobulin protein they make is of one restricted type, referred to as monoclonal protein. The group of neoplastic diseases that form monoclonal proteins are referred to as monoclonal gammopathies. (See Clonal (monoclonal))
Derived from a single clone of cells. Monoclonal antibody. Antibody produced by a clone of lymphoid cells either in vivo or in vitro. In vitro the clone is usually derived from a hybrid of a sensitized spleen cell and continuously growing myeloma cell.
Pertaining to a specific protein from a single clone of cells, all molecules of this protein being the same
Literally, coming from a single clone. A clone is the progeny of a single cell. In immunology, monoclonal generally describes a preparation of antibody that is monogenous, or cells of a single specificity.
Belonging to one and the same clone. The multiple myeloma/plasmacytoma develops from one single malign plasma cell and all cells stemming from this are the same. The mother cell and all of its daughter cells form a cell clone.