NICOLE is a fictional, sentient, portable computer from the Sonic the Hedgehog cartoon series ("SatAM") and Sonic the Hedgehog comic books, owned by Princess Sally Acorn.
Nicole is a fictional character from the Halo universe. She is a Petty Officer Second Class, codenamed Spartan-458, and appears in the video game Dead or Alive 4.
Nicole is a character in the comic strip Doonesbury, known for her radical feminist beliefs.