Definitions for "Parkin"
The northern version of gingerbread and traditionally eaten on Guy Fawkes' night. The recipe varies from county to county and can be cakey or biscuity.
Parkin is an E3 ligase in the ubiquitin-proteasome system. Many mutations in parkin have been associated with a familial form of Parkinson's disease termed autosomal recessive juvenile parkinsonism. How loss of function of parkin leads to dopaminergic cell death in this disease is unclear.
Parkin is a moist and sticky ginger cake made in Northern England. Often associated with Yorkshire, its precise origins are unclear, and it is made and enjoyed in other areas, such as Lancashire. It is traditionally eaten on Bonfire Night, but is also enjoyed year-round.
A protein which is involved in the development of an inherited form of Parkinson's disease which typically presents early in life (under 30 years of age).