Definitions for "PERICENTRIC INVERSION"
A structural alteration to a chromosome that results from breakage, inversion and reinsertion of a fragment that spans the centromere.
An inversion that includes the centromere.
A type of chromosome inversion that includes material on both arms of a chromosome, so that the inverted segment spans the centromere. May lead to miscarriages or handicapped offspring, depending on the exact rearrangement. (Cf paracentric inversion)