cancer treatments that combine the effectiveness of radiation therapy with the targeting capacity of immunotherapy. New radioimmunotherapy regimens are in clinical studies and some treatments, such as Zevalin and Bexxar, have recently been approved.
A cancer treatment in which a radioactive material is attached to a protein that identifies the diseased cells as targets. A monoclonal antibody carries the radiation to the target cells, and the radioactivity kills the cells with which it comes in contact.
a therapy that is prepared by attaching a radioactive isotope to a monoclonal antibody.
a therapeutic method for the treatment of cancer involving the use of monoclonal antibodies, targeted antigens and radionuclides.
The use of radiolabeled antibodies to deliver radiation directly to a tumor.
A treatment that combines the effectiveness of radiation treatment with immunotherapy. The body is given radiolabeled antibodies. These antibodies attach to cancerous cells (thereby alerting the immune system) and weaken them with attached radiation.
Treatment with a radioactive substance that is linked to an antibody that will attach to the tumor when injected into the body.
An exciting new treatment that has shown promise for patients with recurrent follicular NHL who have already had multiple courses of chemotherapy. It combines a monoclonal antibody with radiation therapy.
Radioimmunotherapy (RIT) utilizes an antibody labeled with a radionuclide to deliver cytotoxic radiation to a target cellMilenic DE, Brady ED and Brechbiel MW. Antibody-targeted radiation cancer therapy. Nature Rev Drug Discovery 2004; 3:488-98..