a chromosomal aberration in which the long arms of two acrocentric chromosomes become joined to a common centromere.
abnormality in which individual chromosomes are fused at the centromere
The commonest form of translocation in humans, which occurs between chromosomes which contain no genetic information in their short arms (13,14,15,21 and 22).. The result is a chromosome containing only the long arms of two different chromosomes. Named after William Robertson , who first described them.
The joining of two acrocentric chromosomes at the centromeres with loss of their short arms to form a single abnormal chromosome; in acrocentric chromosomes the centromere is located near the end of the chromosome; acrocentric chromosomes are the Y chromosome and chromosome numbers 13, 14, 15, 21, and 22 Related Terms: chromosome ; deletion ; derivative chromosome ; duplication ; trisomy
A fusion between the centromeres of two acrocentric chromosomes to produce a single metacentric chromosome (see Chapter 5).
A type of translocation exclusive to the acrocentric chromosomes (13,14,15,21,22), in which two chromosomes join at or near their centromeres. This is effectively a fusion between two whole chromosomes rather than an exchange of material as in reciprocal translocation.
A chromosome structural change resulting from centric fusion or centric fission, and resulting in two non-homologous chromosomes attached to the same centromere.
A translocation between two acrocentric chromosomes. The translocation usually involves the loss of the minute short arms and satellites of both chromosomes.
Robertsonian translocation is a common form of chromosomal rearrangement that occurs in the five acrocentric human chromosome pairs, namely 13, 14, 15, 21, and 22. They are named after the American insect geneticist W. R. B.
