Definitions for "S-PHASE FRACTION"
A measure of proliferative activity. The proportion of cells synthesising DNA (ie. in the S-phase of the cell cycle), as estimated by flow cytometry.
an estimate of the percentage of cells in a tissue sample preparing to divide as a measure of its ongoing growth and proliferation
The percentage of cells that are replicating their DNA. DNA replication usually indicates that a cell is getting ready to split into two new cells. A low SPF is a sign that a tumor is slow-growing; a high SPF shows that the cells are dividing rapidly and the tumor is growing quickly.