Definitions for "Sex hormone binding globulin"
a protein produced by the liver that binds with testosterone in the blood, making it available to the body; it more weakly bonds with estrogen.
(SHBG): a protein that binds testosterone to make it unavailable for function; SHBG production is increased by estrogens such as DES. SHBG binds to DHT four times more avidly than to testosterone.