The parasitic, noninfectious stage of the fungus Coccidioides immitis, formed during the organism's growth phase in host tissue.
large, round structure containing endospores; characteristic of Coccidioides immitis in infected host material under direct microscope examination. Spherules do not grow on routine artificial mycology media.
A sporangium-like structure containing endospores that is produced by Coccidioides immitis or Rhinosporidium seeberi.