A mutated gene which produces a product which reverses the effect of a previous specific mutation without actually correcting the original mutation in the DNA can be either intergenic or intragenic.
A gene that exhibits the transformed (malignant) phenotype, usually associated with dominant negative regulation of cell proliferation or cell migration. Often it is mutated or deleted in transformed cells and cancer.
A gene that, when mutated, apparently restores the wild-type phenotype to a mutation at another locus.
a gene that suppresses the phenotypic expression of another gene (especially of a mutant gene)
A gene that reverses the effect of a mutation in another gene.
A gene that can reverse the effect of a mutation in other genes.
genes that normally code for agents that suppress cell growth. Loss of tumour suppressor genes can cause cancer
a gene which helps to reverse the effects of damage to an individual's genetic material, typically effects which might lead to uncontrolled cell growth (as would occur in cancer). A suppressor gene may, for example, code for a protein which checks genes for misspellings, and/or which triggers a cell's self-destruction if too many genetic mutations have accumulated.
A gene that can suppress the action of another gene.
