Definitions for "Synaptophysin"
Nervous System Marker. Synaptophysin is a transmembrane glycoprotein that serves as a component of synaptic vesicle membranes. Antibodies to synaptophysin are utilized as markers of neuroendocrine differentiation. Specificity is greater than that of NSE, and sensitivity is comparable to that of chromogranin.
a protein found on the synaptic vesicle membrane
Synaptophysin is a synaptic vesicle glycoprotein weighing 38kDa. It is present in endocrine cells, the brain, the spinal cord, and adrenal glands. It acts as a marker for neuroendocrine cells.