Organ(s) in which the toxic injury manifests itself in terms of dysfunction or overt disease WHO, 1979 RT receptor
An organ(s) (e.g., liver) or system(s) (e.g., respiratory system) of the human body determined to be susceptible to a noncancer health effect from exposure to a contaminant of concern. A reference dose used to calculate noncancer health risk is normally established based on adverse impact to a target organ or organs from exposure to the contaminant of concern.
The biological organ(s) most adversely affected by exposure to a chemical, physical, or biological agent.
The biological organ(s) most adversely effected by exposure to a chemical substance. This definition archived 9/30/03