An increase in the tendency of the blood to clot, as in 'thrombosis'. In primitive, evolutionary times, a survival advantage for women giving birth, when loss of blood would on average be less, but exacting a price in terms of increased risk of stroke or venous thrombosis. The thrombophilias are implicated in disturbances of pregnancy, including recurrent miscarriage and stillbirth.
increased tendency of blood to clot due to impaired natural anticoagulant or fibrinolytic pathways.
A categorical term for several distinct conditions where there is an increased tendency for excessive clotting.
A hereditary or acquired predisposition to develop blood clots. It is also referred to as hypercoagulable state or hypercoagulability.
a state, either inherited or acquired, characterized by impaired natural anticoagulant or fibrinolytic pathways and a damaged vascular endothelium, and resulting in the abnormal formation of venous or arterial thrombosis. Status can be exacerbated by the existence of more than one predisposing factor (e.g. factor V Leiden mutation and MTHFR heterozygosity)
Thrombophilias are a group of disorders that cause blood to clot too easily. (Read about " Thrombophilia")
Tendency to clot. Often inherited increased clotting tendency, such as factor V Leiden or prothrombin20210 mutation
The tendency to form blood clots (thrombosis). The clots can break off, travel through the bloodstream and lodge in any artery of the body (thromboembolism) and impair the normal circulation within these tissues. Thrombophilia can be inherited or acquired.
Thrombophilia is the propensity to develop thrombosis (blood clots) due to an abnormality in the system of coagulation.