To or in the upper part of a town; as, to go uptown.

Situated in, or belonging to, the upper part of a town or city; as, a uptown street, shop, etc.; uptown society.

a residential part of town away from the central commercial district

Uptown is a neighborhood located in Harrisburg, Pennsylvania. Its southern boundary is the Midtown neighborhood; northern boundary is the city line with Susquehanna Township; western boundary is the Susquehanna River; eastern boundary is the old Main Line (Pennsylvania Railroad), which is currently utilized by Norfolk Southern and Amtrak. Its zip code is 17110.

Uptown (업타운) is a Korean hip hop and R&B group which first debuted in 1997. The group's four original members included Chris Jung, Carlos Galvan, Steve Kim and Tasha Reid. The group underwent several lineup changes and then disbanded in 2000.

Uptown is an alternative weekly arts and entertainment newspaper in Winnipeg, Manitoba, Canada. Like most alternative weekly newspapers in Canada, Uptown includes articles regarding the arts and entertainment, CD reviews, concert reviews, book reviews and extensive current events listings. However, unlike others in its genre (such as Now Magazine, Voir and the Georgia Straight), Uptown generally does not provide any substantial coverage of current issues events apart from occasional columns concerning local news.

"Uptown" was the lead single in the U.S. to Prince's third album, Dirty Mind. Beginning with a lone drum intro, the track explodes into the keyboards of the chorus. The verses feature a more prominent funk guitar.

Area "upriver" from the French Quarter