A disease in which histiocytes are the principal cells involved. Langerhans cell histiocytosis is a neoplastic proliferation of histiocytes that involves the skin, bone, brain and other organs.
(Multiple sites) Rapidly progressive malignant cancer infiltrating many parts of body, often including the lungs, liver, spleen, and central nervous system. Special Diagnostics: radiograph and biopsy.
abnormal appearance of histiocytes in the blood. (Histiocytes are produced by the bone marrow and are normally immobile until stimulated by inflammation. They are a type of antigen presenting cell.) cutaneous – benign proliferation of nodules in or under the skin malignant – a rapidly invasive proliferation of neoplastic (new growth) histiocytes. No known treatment, always fatal. systemic – proliferation of histiocytes invading the skin and lymph nodes. Can go into remission for years, or progress to the malignant form. Can be treated, but not cured.
a blood disease characterized by an abnormal multiplication of macrophages
Abnormal proliferation of histiocytes (immune system cells). Common symptoms include bone tumors and skin rashes. If histiocytosis affects the eyes, it causes bulging.
A rare and frequently fatal blood disease that affects the body's immune system (Read about " The Immune System"), allowing a type of white blood cell called a histiocyte to multiply wildly and attack vital body organs. Its cause is unknown, and its progression is unpredictable.
A rare and often fatal blood disease. A type of white blood cell called a histiocyte grows wildly and attacks body organs.
Though histiocytosis can refer to any of several specific diseases, the term is generally used to refer to a rare blood disease that is caused by an excess of white blood cells called histiocytes. The histiocytes cluster together and can attack the skin, bones, lung, liver, spleen, gums, ears, eyes, and/or the central nervous system. The disease can range from limited involvement that spontaneously regresses to progressive multiorgan involvement that can be chronic and debilitating.