Widespread distribution of and damage to white matter of the brain due to rotational shearing forces coincident with head trauma.
Widespread and patchy shearing of the axons (nerve cells) which interconnect areas of the brain. Such damage is characteristic of severe CLOSED HEAD INJURY (qv).
The widespread structural injury and disruption of axons, the wires of communication that exist between brain cells, that results from the forces of trauma.
A shearing injury of large nerve fibers (axons covered with myelin) in many areas of the brain. It appears to be one of the two primary lesions of brain injury, the other being stretching or shearing of blood vessels from the same forces, producing hemorrhage.
Damage to the axons of many nerve cells that lie in different parts of the brain.
A shearing of large nerve fibres in many areas of the brain rather than one specific location.
Widespread injury to cells in many areas of the brain other than in one specific location.
widespread injury (tearing) to the axon, the cylindric extension of a nerve cell that conducts impulses away from the neuron cell body. Axons may be bare or wrapped in myelin. Diffuse axonal injury is a consequence of shaken baby syndrome.
the shearing (tearing) of the brain's long connecting nerve fibers (axons) that can occur with severe brain injury.
Diffuse axonal injury (DAI) is one of the most common and devastating types of brain injury (Iwata et al., 2004), occurring in almost half of all cases of severe head trauma (Park and Hyun, 2004). It is a type of diffuse brain injury, meaning that damage occurs over a more widespread area than in focal brain injury. DAI, which refers to extensive lesions in white matter tracts, is one of the major causes of unconsciousness and persistent vegetative state after head trauma (Wasserman, 2004).