a line of cells derived from disaggregated pre-implantation embryos that possess totipotent nuclei that have not undergone differentiation into specialized tissue cells and are capable of forming an entire individual.
(ES cells). Stem cells have the dual capacity to self-replicate and differentiate into several specialized derivatives. ES cells are pluripotent cells that are derived from pre-implantation stage (usually blastocyst) mammalian embryos. Mouse ES cells can be propagated and manipulated in vitro, yet still retain their pluripotency.
See: stem cell
Cells in a developing organism that have not yet reached their differentiated states (the point at which they specialized to form a particular tissue or function.).
Stem cells taken from embryos that have been fertilized in vitro.
ES cells are pluripotent cell lines established, usually, from the inner cell mass of the blastocyst stage of development. Within the population of cultured ES cells are cells that can produce more ES cells, or under conditions of differentiation, give rise to collections of cells that include most, if not all cell types that can be found in a postimplantation embryo, fetus, or developed organism, but not trophoblast or placenta. To date no ES cells cultured in vitro can give rise to developed organisms or even developed organs. A test of pluripotency of mouse ES cells is to inject them into blastocysts prior to implantation; the progeny of these cells can participate in all germline and somatic tissues along with host blastocyst-derived cells.
Primitive (undifferentiated) cells from the embryo that have the potential to become all cell types found in the body. Embryonic stem cells (ES) are found in the inner cell mass of blastocysts (a very early embryo consisting of approximately 150 cells). Scientists are working diligently to develop methods that can easily identify embryonic stem cells, and control how to change them into specific cells types (brain cells, heart cells, or pancreas cells, for example).
Undifferentiated cells in an embryo that are able to multiply and become differentiated into any type of cell in the body.
Cell lines derived from early embryos that have the potential to differentiate into all types of somatic cells as well as to form germ line cells, and hence whole animals, when injected into early embryos.
A cell in the early embryo which is totipotent in terms of cellular fate.
Cells that are removed from the early embryo and are able to become any of the 210 cell types found in the human body. Researchers are looking at the great potential stem cells have in developing new treatments for disease and injury.
Cells derived from an embryo that have the ability to become any cell of the organism.
Self-renewing, undifferentiated stem cells removed from the inner cell mass of a blastocyst and grown in culture.
Embryonic stem cells are the "blank slates" of an organism, capable of developing into all types of tissue in the body. Scientists have long been interested in the therapeutic potential of embryonic stem cells, which may be used someday to create new tissues for organ transplants and replacements for cells destroyed by diseases like diabetes or trauma like spinal cord injuries.
Very primitive cells that develop within days of ova fertilization with the potential to develop into all of the body's cell types.
Undifferentiated cells from the embryo with the potential to become various specialized cell types.
Blank, unspecialized cells found in a blastocyst. These cells have the ability to grow into any and every cell in the body. They also have the ability to continue to multiply and exist indefinitely. Human embryonic stem cells are also known as â€œhESCâ€ or â€œhuman ES cellâ€.
Primitive (undifferentiated) cells from the embryo that have the potential to becomea wide variety of specialized cell types.
primitive (undifferentiated) cells that have the potential to become a wide variety of specialized cell types (i.e., cardiac myocytes, neuronal, pancreatic). They are pluripotent cells derived from the inner cell mass of a blastocyst. Embryonic stem cells are NOT embryos and cannot become a complete organism.
Stem cells that come from human embryos. Stem cells from embryos are not used for marrow or blood stem cell transplants.
Early embryonic cells (usually mouse cells) that can be genetically manipulated by researchers and then implanted into embryos to produce transgenic animals (usually mice) with predetermined genetic mutations.
Undifferentiated cells derived from the inner cell mass of a developing blastocyst. Embryonic stem cells are self-renewing and pluripotent - that is, they are capable of forming all the different types of cells found in the body, except the placenta and other supporting tissue necessary for foetal development.
Cells that can produce every type of cell in the body. They are made from a blastocyst.
Primitive (undifferentiated) cells derived from inner cell mass of a blastocyst-stage embryo that have the potential to become a wide variety of specialized cell types (pluripotent).
Embryonic stem cells emerge in the first five to seven days of the embryo's development. They have the potential to become every cell of the body.
Pluripotent stem cells taken from the inner cell mass of the growing blastocyst.
An embryonic cell that can replicate indefinitely, transform into other types of cells, and serve as a continuous source of new cells.