USS Lawrence (DDG-4), named for Captain James Lawrence USN (1781-1813), was a Charles F. Adams class guided missile armed destroyer in the United States Navy.

Five United States Naval ships have borne the name USS Lawrence for James Lawrence.

The third USS Lawrence (DD-8) was a destroyer in the United States Navy.

The first USS Lawrence was one of two 493-ton Niagara-class brigs built at Erie, Pennsylvania, by Adam and Noah Brown under the supervision of Sailing Master Daniel Dobbins and Captain Oliver Hazard Perry, for United States Navy service on the Great Lakes during the War of 1812.

The fourth USS Lawrence (DD-250) was a Clemson-class destroyer in the United States Navy during World War II. She was named for James Lawrence.

The second USS Lawrence was a brig in the United States Navy.