USS Gridley (DLG-21), a Leahy-class guided missile frigate, was the third ship of the United States Navy to be named for Charles Vernon Gridley, who distinguished himself with Admiral David Farragut's force at the Battle of Mobile Bay on 5 August 1864.

The first USS Gridley (DD-92) was a Wickes-class destroyer in the United States Navy during the World War I. She was named in honor of Charles Vernon Gridley.

Four United States Navy ships have been named USS Gridley in honor of Charles Vernon Gridley (1844–1898), an officer in the Navy during the American Civil War and the Spanish-American War.

The fourth USS Gridley (DDG-101) will be the fifty-first Arleigh Burke-class destroyer in the United States Navy. Gridley is named after Captain Charles Gridley, Commander of Admiral George Dewey's flagship Olympia, (Flag Captain) and recipient of Admiral Dewey's famous command, "You may fire when you are ready, Gridley" in the Battle of Manila Bay during the Spanish-American War.

The second USS Gridley (DD-380) was the lead ship of her class of destroyers in the United States Navy. She was named for Charles Vernon Gridley.