Cathedral High School is a Roman Catholic college-preparatory High School in Springfield, Massachusetts. Opened in 1883 by the Sisters of Saint Joseph behind the diocese's Saint Michael's Cathedral, its current facility has been at 260 Surrey Road since 1959 in one of the city's residential neighborhoods. It is one of four Catholic High Schools within the Springfield Roman Catholic Diocese.

Cathedral High School is a private, Catholic Institution in Indianapolis, Indiana, United States. It serves over 1,200 students in grades 9 to 12.

Cathedral High School is a private Catholic all boys school in Los Angeles, California. It was founded by Archbishop John J. Cantwell as the first Los Angeles Archdiocesan high school for boys in the fall of 1925.

Cathedral High School is a Roman Catholic coeducational parochial high school located in St. Cloud, Minnesota. One of the four high schools in the St.

Cathedral High School is a Canadian Secondary School in Hamilton, Ontario under the jurisdiction of the Hamilton Wentworth Catholic District School Board. It is the only Catholic High School in Hamilton to run the French Immersion program. The School colours are blue and white.