Lafayette High School is the oldest public school in Buffalo that remains in its original building; a stone, brick and terra-cotta structure in the French Renaissance Revival style, by architects August Eisenwein and James A. Johnson. Although classes began off-site during construction of the school, the building was completed, and graduated its first class, in 1903.

Lafayette High School (Commonly referred to as LHS) is a Rockwood School District secondary school in Wildwood, Missouri. Lafayette High School is the only high school in Missouri to earn top 10 recognition in all five areas of the MAP test and has 23 National Merit Recognized students for the 2005-2006 school year. It is also a two time Missouri Gold Star School and National Blue Ribbon School.

Lafayette High School is a high school located in Lafayette, Louisiana.

Lafayette High School is a public secondary school in James City County, Virginia, just outside the city limits of Williamsburg, Virginia. It is part of Williamsburg-James City County Public Schools and is located on 4460 Longhill Road.

Lafayette Senior High School (LHS) is a public high school located in Lexington, Kentucky. The school is one of five high schools in the Fayette County Public Schools district. It is among the largest high schools in Kentucky.

Lafayette High School is a high school (grades 9-12) in St. Joseph, Missouri. It was established in 1917 (originally as "North High School"), and at the time was the third high school in the city http://www.sjsd.k12.mo.us/Schools/Lafayette/lhshistory/lhshistoryhome.htm.