A congenital disorder caused by an extra chromosome 21 in some or all cells. It causes a variable number and degree of abnormalities, including retarded growth, mental retardation, a short nose, prominent epicanthic folds on the eyelids, a protruding lower lip, and other physical features having varying degrees of deviation from the normal. Called also mongolism, trisomy-21 and trisomy 21 syndrome.
A congenital abnormality in which the baby is born mentally retarded, with an average IQ of 50 - 60 and with physical deformation of the face (low set ears, sloping forehead, mongoloid eyes), and shortness of stature. Downs syndrome is caused by an extra chromosome 21 present in the G group. In a small percentage of cases it can be caused by the switching of chromosomes 14 or15 in the D group or chromosome 21 or 22. Down's syndrome occurs in about 1 in 650 births, and is more commonly associated with children of mother's over the age of 35. Incidence in children of mothers over the age of 40 can be as high as 1 in 80. Down's syndrome can be detected prenatally through amniocentesis. The mortality rate is high within the first few years. Down's syndrome is also known as mongolizm, trisomy 21 or trisomy G syndrome.
Condition associated with a chromosome abnormality, usually trisomy of chromosome 21. See Trisomy. Symptoms and findings include a small, flattened skull, short, flat-bridged nose, an abnormal fold at the inner edge of the eyes, short fingers and toes, and moderate to severe mental retardation.
Inherited chromosomal disorder with one extra chromosome number 21. The victim displays abnormal physical features and moderate to severe mental retardation.
a genetic abnormality caused by an extra chromosome 21, which causes mental retardation and other physical abnormalities
A disorder caused by a chromosomal problem and resulting in mental delays and physical challenges .
See: Down syndrome
(downs SIN-drome) Genetic disorder that is caused by the presence of an extra copy of a particular chromosome and is characterized by a broad skull, blunt facial features, short stature and learning difficulties. Also called Down syndrome.
A genetic disorder caused by the presence of an extra chromosome 21.
A chromosome abnormality in which there are 3 copies of chromosome 21 instead of 2. It is also called Trisomy 21. The condition is characterised by distinctive facial features and varying degrees of learning difficulties and is often associated with lung and heart problems.
A disorder caused by an extra chromosome of the genes causing mental and physical developmental disabilities in the offspring.
a congenital disorder caused by having an extra 21st chromosome; results in a flat face and short stature and mental retardation
An abnormality in the chromosomes that is characterized by varying degrees of mental retardation and physical malformations.
A number of problems in development occurring from a chromosomal abnormality. These include moderate to severe mental retardation, short fingers, and a mongoloid appearance.
A syndrome characterised by behavioural, physiological and mental defects due to chromosome mutation. The commonest cause is trisomy for chromosome 21.
A congenital condition characterized by mental deficiency and related to the tripling of certain human chromosomes. Effluent - Liquid or gaseous radioactive discharge from a nuclear reactor.
Congenital abnormality caused by an additional chromosome 21 (trisomy 21), resulting in distinctly recognisable features and mental retardation. | Back to previous page
The preferred term used for what was once known as Mongolism, a common form of mental retardation caused by a chromosomal abnormality. In addition to mental deficiency, the disease is characterized by a broad face with widely spaced, slanting eyes, small flat-backed head, lax joints, flabby hands, small ears and congenital abnormalities of the heart.
A form of mental disability that is the result of chromosomes dividing improperly during fetal development. "A person with Down's Syndrome" is much preferred to the term "mongoloid."
The most common chromosomal abnormality, Down's syndrome causes mild to severe learning disabilities, as well as other physical problems such as heart defects.
A congenital abnormality caused by a mutation of the DNA, commonly resulting in 47, not 46 chromosomes in each cell; people affected by Down's Syndrome suffer from mental retardation, learning difficulties, loss of hearing and speech impediment.
A person born with chromosomal differences that often results in developmental disabilities.
A congenital condition in which some or all of the body cells have three copies of chromosome 21. This form of trisomy is associated with an increased risk of leukemia.
a condition where an individual has an extra copy of chromosome 21, resulting in mental retardation, characteristic body shape and abnormalities of the heart and other organs.
due to an extra chromosome. (21st pair)
Relationship to Gluten Sensitivity / Celiac Disease"Patients with Down syndrome have an incidence of celiac disease of at least 7 percent..."