Also called "clinical studies." Research studies with people. Each trial tries to answer specific scientific questions and to find better ways to prevent, detect, or treat diseases or to improve care.
Studies which compare a well-known, or standard, treatment with a newly developed treatment. Clinical trials are usually done in three phases. Phase I tests the safety of the treatment on a small number of patients. Phase II assesses the effectiveness of the treatment and usually involves a larger group of people. Phase III provides in-depth information about the effectiveness and safety, by comparing experimental treatment with the standard protocol. Phase III trials usually involve several thousand patients nationwide. Randomized clinical trials, considered the "gold standard" of scientific research, involve study participants who are randomly assigned to different treatment groups and then compared.
Medical research studies conducted on human subjects to answer scientific questions and to find better ways to prevent, detect or treat the disease.
scientific studies comparing two or more treatments.
Carefully controlled tests that are conducted in humans to learn the effectiveness and safety of new medical products (such as all new drugs) and techniques.
clinical trials: research studies to test new therapies, including new surgical approaches and medications
Drug testing in humans to assess safety, side effects and efficacy.
Studies conducted on patients with cancer or other diseases, usually to evaluate a promising new treatment. Each study is designed to answer a specific question and find better ways to treat patients.
An investigation in which the effectiveness and safety of new medications or treatments are tested. In the United States , all drugs must undergo three phases of clinical trials before being approved for general use.
The testing new of drugs and vaccines by administering them to people in order to demonstrate their safety and effectiveness to regulators. A key part of the approval process.... more on: Clinical trials
Once a new medicine is discovered, it has to be proven that it really works. Clinical trials are performed on people, typically in hospitals, where first of all healthy people get the new medicine to see if there are any side-effects in a Phase I trial. Then, in a Phase II trial, a small group of people with the disease get the drug to see if they get better taking the drug. If all these tests are successful, a big Phase III trial will be held where hundreds or even thousands of people with the disease get the medicine and a large group of people get a placebo, which looks and tastes exactly the same as the real pill, but there is no active ingredient inside. If the big clinical trial shows that patients treated with the real medicine get better more often than the people who took the placebo, then the company who invented the medicine can start to prepare to sell it to everyone.
Research studies performed on patients to determine effectiveness of new drugs or other medical treatments. Patients who volunteer for clinical trials must read and sign a statement indicating "informed consent." For research purposes, some patients may receive a placebo in a clinical trial, instead of the drug under investigation.
Research studies that involve patients. Biotechnology companies typically use clinical trials to assess the efficacy and safety of new therapies and to answer scientific questions. Typically, there are 3 phases during a clinical trial. Phase I is designed to evaluate the safety of the product in humans; phase II analyses the effects of dose escalation, and phase III definitively evaluates the clinical efficacy of the product.
research studies that search for and test new treatments on people.
clinical trial is conducted in order to test a new discovery against the standard available therapy. These human studies are conducted only if extensive laboratory studies suggest the treatment will work.
Clinical trials are one of the final stages of a long and careful research process to help patients live longer, healthier lives. They help doctors and researchers find better ways to prevent, diagnose, or treat diseases. Clinical trials test new types of medical care, like how well a new cancer drug works. The trials help doctors and researchers see if the new care works and if it is safe. They may also be used to compare different treatments for the same condition to see which treatment is better, or to test new uses for treatments already in use.
Human experiments conducted by researchers that test the value, safety and efficiency of various treatments, such as drugs.
An internationally recognized research protocol designed to evaluate the efficacy or safety of drugs, vaccines, or other therapeutic agents, and to produce scientifically valid results
Studies that investigate different therapies or combinations of treatments in order for researchers to improve the best treatment options for patients. They are an important part of the process of understanding diseases, and have been instrumental in providing information to the Food and Drug Administration for approval of new therapies. read more...
These trials are used to assess the effectiveness of different forms of treatment, often by comparing the effects of a new treatment with one whose effects are already known.
are designated as phase I, II, or III, based on the type of question and number of people in the study: Phase I clinical trials researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects. Phase II clinical trials the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety. Phase III clinical trials the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely. (text modified from NIH Clinical Trials site)
research studies to test new drugs or other treatments to compare current, standard treatments with others that may be better. Before a new treatment is used on people, it is studied in the lab. If lab studies suggest the treatment will work, the next step is to test its value for patients.These human studies are called clinical trials. The main questions the researchers want to answer are: Does this treatment work? Does it work better than the one we're now using? What side effects does it cause? Do the benefits outweigh the risks? Which patients are most likely to find this treatment helpful? During the course of treatment, the doctor may suggest looking into a clinical trial. This does not mean that the patient is being asked to be as a human "guinea pig." A clinical trial is done only when there is some reason to believe that the treatment being studied may be of value. Nor does it mean that the case is hopeless and the doctor is suggesting a last-ditch effort. Clinical trials are carried out in steps called phases. Each phase is designed to answer certain questions. To learn more about clinical trials, call the National Cancer Institute at 1-800-4-CANCER.
Clinical trials are research studies to determine whether new drugs or treatments are safe and effective. These trials are used to confirm effectiveness, monitor side effects, and compare the drug or treatment to commonly used treatments. Other studies are conducted after the drug or treatment has been marketed. These studies determine the effect of the drugs or treatments in various populations, and monitor any side effects from long-term use. For more information on clinical trials, check the National Institute of Health: http://www.niaid.nih.gov/clintrials/clinictrial.html.
Research studies that involve patients. Each study is designed to find better ways to prevent, detect, diagnose, or treat disease. See also Drug Development Process.
As used in this workshop summary, research with human volunteers to establish the safety and efficacy of a drug, such as an antibiotic or a vaccine.
prospective studies in humans that compare the effectiveness and value of a potential new drug or therapy in one group against a control group before the drug or therapy is made available to the general population
Carefully planned and monitored experiments to test a new drug or treatment.
Tests on informed and consulting volunteers. Health Canada will permit clinical trials only if they are deemed safe and will prove something medically worthwhile. Proposed trials also require approval from independent ethics boards at the hospital or research facility where the work is to proceed.
Research studies that test new medical treatments and other interventions work in people. Tests may be preventative, diagnostic or therapeutic.
A scientifically designed and executed investigation of the effects of a drug (or vaccine) administered to human subjects. The goal is to define the safety, clinical efficacy, and pharmacological effects (including toxicity, side effects, incompatibilities, or interactions) of the drug. The U.S. government, through the FDA , requires strict testing of all new drugs and vaccines prior to their approval for use as therapeutic agents.
Research studies in which a treatment or therapy is tested in people to see whether it is safe and effective.
Research studies conducted in humans to answer specific health-related questions. A common type of clinical trial is the interventional clinical trial, in which the safety and effectiveness of a new type of investigational therapy is compared to that of other commonly used therapies or, in some cases, no therapeutic intervention.
Clinical trials are the way of testing drug safety, efficacy, and pharmacology. Usually clinical trials are done for the purpose of obtaining approval from the FDA to sell the product as a medication.
Experiments designed to test the effectiveness of a treatment or intervention. The term "clinical trial" often refers to specific experiments to test a new compound for potential use as a pharmaceutical or clinical agent. To conduct this type of clinical trial, an Investigational New Drug (IND) Application must be filed with the Food and Drug Administration (FDA). If the FDA accepts the IND, clinical trials in human subjects can be conducted. There are several phases of clinical trials before a drug is approved by the FDA.
experimental drugs which have shown promise in test-tube studies proceed through several stages of clinical trials: phase I trials establish that a drug is safe for humans to take; phase II trials examine whether the drug is effective against HIV; phase III trials are the final step before approval, looking at effectiveness, safety and side effects in large numbers of people.
Testing of a drug compound in humans to ensure that the drug is efficacious and safe to humans. Trials are generally controlled by the Food and Drug Administration (FDA) and may begin once such characteristics have been demonstrated in animals.
Research studies to test new treatments, or approaches, which might provide better results than current methods. Strict rules are followed to make sure patients are well informed about the purpose, risks and benefits of any study before they agree to join a clinical trial.
Research studies of new cancer treatments and investigative drugs or of different dosages of standard drugs used to compare a standard treatment with one that may be better.
Research to test new drugs or treatments to compare to others to see which may be better.
The process by which new cancer treatments are tested in humans. Clinical trials are conducted after preliminary testing has shown that a new treatment might be effective. For more information see What Are Clinical Trails All About booklet.
Research study conducted with healthy subjects or patients usually to evaluate a new treatment of drug
Tests of new and promising ways to treat cancer. The goal of all clinical trials is to find better treatments to fight cancer. Clinical trials can test new surgical procedures, radiation therapies, and drugs.
Offer patients new or experimental treatment programs and special agents for the treatment of cancer and blood diseases. Participation is 100% voluntary. Clinical trials involve these phases
Medical testing of human subjects to determine the effectiveness of pharmaceutical products or treatment methods.
Research studies used to evaluate new ways to treat cancer.
Studies that provide data from direct medical care to assess the effectiveness of treatments.
The testing of an experimental drug in humans. Once clinical trials demonstrating safety and efficacy are completed, a pharmaceutical company can apply for approval for public use of the drug.
evaluation of potential new treatments, using patients under strictly controlled conditions.
are used to determine whether new drugs or treatments are both safe and effective. Carefully conducted clinical trials are the fastest and safest way to find treatments that work in people. Trials are in four phases: Phase I tests a new drug or treatment in a small group; Phase II expands the study to a larger group of people; Phase III expands the study to an even larger group of people; and Phase IV takes place after the drug or treatment has been licensed and marketed. 5
Long-term research studies that test cancer treatment.
Studies to determine the best drugs or means of administering them; all participants receive standard of care.
A scientific study to determine the safety and effectiveness of a new treatment. New treatments are tested on people only after they are found to be safe and effective in both test tube and animal studies.
Research studies designed to find more effective treatments and better ways to use current treatments. Participation in treatment studies is an option for many patients with cancer. In some studies, all patients receive the new treatment. In others, doctors compare different therapies by giving the new treatment to one group and the standard therapy to another group. In this way, doctors can compare different therapies.
The procedure in which new cancer treatments are tested. The treatment is evaluated for its effectiveness in reducing or eliminating disease. A clinical trial may be done by the National Cancer Institute, a drug company or a hospital to determine the most effective dose of a drug, to compare different combinations of treatments, or to determine the effect of the drug on a tumor.
A scientific test of the effectiveness and safety of a therapeutic agent(drugs, vaccines) using consenting human subjects.Most trials are designed to investigate better ways to prevent, detect, diagnose, or treat cancer and to answer scientific questions.
Controlled scientific tests involving human beings that compare new methods of cancer treatments against older methods.
clinical research involving large numbers of people who volunteer to test whether a way to prevent cancer or to treat cancer will really work..
Research studies that test potentially useful new medical treatments on human subjects.
Studies that evaluate new drugs or new types of treatment.
Experiments involving humans.
Studies that test new cancer therapies.
research studies which test new diagnostic and/or treatment regimes and compare these treatments to current, standard treatments. Before a new treatment is used on humans, it is studied in a scientific lab. If lab studies suggest the treatment is effective, it is tested for patients.
Scientifically controlled research studies involving people. Such studies are used to determine the effectiveness of a new treatment, pharmaceutical, compare standard medications or procedures with others that may be equal or better.
Testing of a drug compound or medical device in humans to ensure that the drug is efficacious and safe. Clinical trials are controlled by the Food and Drug Administration (FDA) in the United States. Approval by the FDA to conduct a well-defined clinical trial may be granted after safety has been demonstrated in non-clinical studies.
Studies of promising new or experimental treatments in patients. Clinical trials are only done when there is some reason to believe that the treatment being studied may be valuable to the patient.
Randomized and controlled research studies involving large groups of patients. Designed to answer questions regarding the optimal treatment of disease.
Studies conducted with cancer patients, usually to evaluate a promising new treatment. Each study is designed to answer questions to find better ways to treat patients.
Testing of a medical device on patients in accordance with a specific study plan approved by the regulatory agency the country in which the trial is being carried out and relevant ethics committees.
Studies designed to test new ways to prevent or manage disease or its symptoms.
The last phase in the development process for new drugs in order to determine the effect on patients in real life studies.
The investigational use of a new drug in humans: Phase I clinical trials test a drug for safety, Phase II clinical trials test a drug for efficacy and safety in a relatively small sample of patients, and Phase III clinical trials test the drug for efficacy in larger numbers of patients and compares the drug with conventional therapies.
the systematic evaluation of new medical treatments which have shown promise in animal and laboratory tests.
Carefully planned and controlled studies that are carried out with groups of volunteers. They test the effectiveness and safety of new treatments, medical products or techniques.
research studies to test new drugs or procedures or to compare current standard treatments (medications, procedures) with others that may be equal or better.
Programs created to test the safety and effectiveness of new products. Companies typically use volunteers to test the product - and monitor them for success with the product and any side effects.
Clinical trials undertake experimental study of human subjects. Trials may attempt to determine whether the finds of basic research are applicable to humans, or to confirm the results of epidemiological research. Studies may be small, with a limited number of participants, or they may be large intervention trials that seek to discover the outcome of treatments on entire populations. The "gold standard" clinical trials are double-blind, placebo-controlled studies which employ random assignment of subjects to experimental and control groups unknown to the subject or the researcher.
the testing and observation of the treatment of disease in patients (as opposed to experimental or laboratory testing)
Controlled research studies for cancer treatment, in order to determine the best possible treatment for a specific condition. take place in many hospitals and cancer centers across the country, with sponsorship and review by the National Cancer Institute. In these clinical trials, doctors use the newest treatments to care for cancer patients. By agreeing to participate in a clinical trial, the patient agrees to follow the protocol of the specified drugs and to cooperate with the scientists to find new, improved treatments for cancer. Participation is voluntary in all clinical trials and patients may drop out of a clinical trial if they wish.
A medical product marketed anywhere in the world goes through lengthy testing, which is heavily regulated by the appropriate authorities. Early in the process the product undergoes chemical and animal testing. Finally after years of study the product is given to humans in carefully monitored clinical trials. When the trials are complete, a license application is submitted to the appropriate authorities. The study is reviewed, and it is then determined if the product is suitable and safe for human consumption. The entire process typically takes 10 years, and about £150 million to fund.
Medical studies of patients that evaluate the effectiveness of treatment.
research programs conducted with patients to evaluate a new medical treatment, drug or device. The purpose of clinical trials is to find new and improved methods of treating different diseases and special conditions.
Trials to evaluate the effectiveness and safety of medications or medical devices by monitoring their effects on large groups of people. See the entire definition of Clinical trials
Research studies test new drug treatments and compare them to current, standard treatments. Before a new treatment is used on people, it is tested in the lab. If lab studies suggest the treatment works, it is tested on patients. These human studies are called clinical trials.
These studies involve patients in the testing of new treatments and therapies and are part of the drug approval process in America. A clinical trial, which typically has three stages, or phases, gauges a drug's safety, effectiveness, dosage requirements, and side effects. Patients must meet certain criteria to be enrolled in a clinical trial (which is determined for each individual study), and participation in a study is voluntary. Clinical trials are sponsored by pharmaceutical companies, government agencies, and other healthcare-related organizations; many are based at research universities or hospitals. A set of rules, or protocol, is established for each trial.
Carefully controlled studies that are conducted in humans who volunteer to test the effectiveness and safety of new drugs, medical products or techniques. All drugs in the United States undergo three phases of clinical trials before being approved for general use.
a systematic evaluation of a possible new cancer treatment conducted with cancer patients after the treatment has had some benefits in animal testing or laboratory testing.
part of the process of testing new drugs and vaccines for efficacy and safety, by giving the product under controlled conditions.
Research studies that evaluate the effectiveness of new treatment or disease prevention methods on patients.
Tests of a treatment's effects in humans. Clinical trials help researchers find out whether a promising treatment is safe and effective for people. They also tell scientists which treatments are more effective than others.
studies that involve patients aimed at finding better ways to prevent, detect, diagnose, or treat cancer.
Part of the process of testing new vaccines and drugs for safety and effectiveness by giving the product to people under carefully monitored conditions
Research studies conducted with actual patients to examine the safety and effectiveness of new drugs or treatments.
research studies that test new treatments such as new drugs, new combinations of drugs, or new methods of giving drugs.
Medical research studies conducted with volunteers. Each study is designed to answer scientific questions and to find better ways to prevent or treat cancer.
Research studies that involve people. Each study tries to answer scientific questions and to find better ways to prevent or treat cancer.
Tests on human subjects of existing, new, or experimental treatments.
Clinical trials test new treatments (often referred to as “investigational drugs or biologics” because they have not yet been approved by the FDA) in people with diseases such as cancer. Clinical trials test unapproved drugs, new combinations of drugs, or new treatment strategies to determine whether these promising alternatives are safe and effective and may provide a better treatment option than current therapies. Data gathered during clinical trials is then reviewed by the FDA to determine approval.
Research studies in which data from direct medical care is used to assess the effectiveness and safety of treatments or other interventions.
Organized, carefully planned, research studies conducted on people to find better ways to diagnose, prevent and treat disease. The studies are done on human patients to evaluate whether the new treatment, procedure or device is safe and effective. During the study, patients are usually assigned at random to either a control or treatment group in order to avoid bias and assure more objective results. People in the treatment group receive the treatment, procedure or device; the control group participants receive a more standard treatment, no treatment or a placebo (a look-alike that has no active drug).
Research studies that involve patients. Each study is designed to find better ways to prevent, detect, diagnose, or treat cancer and to answer scientific questions.
Cancer research studies often include the testing of new drugs or treatments, to compare them to current, standard treatments. Before a new treatment is used on people, it is studied in a laboratory environment. If lab studies suggest that a treatment works, it is tested with cancer patients. These human studies are called clinical trials.
Research to discover methods and medication to prevent cancer.
Trying medicine on humans to see how effective and safe they are for future use.
Studies of new medical treatments. Studies answer scientific questions and lead to better ways to treat patients.
Organized studies that test the value of various treatments, such as drugs or surgery, in human beings.
organized research studies that provide clinical data aimed at finding better ways to prevent, detect, diagnose, or treat diseases.
Testing of new drugs in human subjects to prove safety and efficacy prior to the drugâ€(tm)s approval for marketing.
Studies which test experimental medicines in humans, in order to establish that they are safe and effective. Clinical trials are staged in 'phases', beginning with small numbers of people, then being tested more widely as data on safety and efficacy is established.
A research study that tests how well new medical treatments or other interventions work in people. Each study is designed to test new methods of screening, prevention, diagnosis, or treatment of a disease.
A Clinical trial is a prospective, organized, systematic exposure of subjects to an intervention of some kind (drug, surgical procedure, medical device, etc.) to answer some question about the intervention.