(Lodosyn): A drug that is usually given in combination with a Parkinson's drug called levodopa; the combination is called Sinemet. Carbidopa improves the effectiveness of levodopa and can be used to reduce the side effects of levodopa.
a drug given in combination with levodopa in order to treat Parkinson's disease symptoms. Carbidopa reduces the side effects associated with prolonged levodopa use.
a drug that is used in combination with levodopa (Sinemet) to treat PD. Carbidopa prevents levodopa from being metabolized in the body, allowing more levodopa to reach the brain.
The ingredient in Sinemet which prevents the breakdown of the levodopa in the body before it can reach the brain.
administered with L-dopa in the treatment of Parkinson's disease to increase the amount of L-dopa available for transport to the brain.
A drug that allows more levodopa to get into the brain to be converted into dopamine. It prevents the enzyme AADC from normally breaking down levodopa in the blood. Levodopa therapy today is administered in a combination tablet with carbidopa.
The decarboxylase inhibitor that is co-administered with levodopa in Sinemet
a drug used in combination with levodopa in the treatment of Parkinson's which prevents levodopa from being metabolized in the body, thus allowing more levodopa to reach the brain.
A drug that inhibits the action of amino acid decarboxylase (AADC), an enzyme responsible for the breakdown of levodopa in the blood before it reaches the brain. Carbidopa allows more levodopa to cross the blood-brain barrier to be converted into dopamine. Virtually all levodopa therapy to day is administered in a combination pill with Carbidopa.
A drug combined with levodopa to slow the breakdown of the levodopa by dopa decarboxylase, which is a naturally occurring enzyme that decreases levodopa's availability for entry into the brain
A drug often used in conjunction with levodopa—as in the drug Sinemet—to increase levodopa's efficacy by allowing more to reach the brain. Carbidopa also reduces levodopa's unpleasant side effects such as nausea.
Carbidopa (MK-486) is a drug given to people with Parkinson's disease in order to inhibit peripheral metabolism of levodopa.