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Keywords:
Nonfunctional,
Inactivated,
Transcribed,
Mutation,
Gene
An inactivated and hence nonfunctional copy of a gene.
A nonfunctional gene sequence that is related to a known gene but cannot be transcribed or translated due to mutations.
A gene showing significant sequence homoplasy (75%) to a functional gene, but which has lost any normal function, often through gaining internal stop codons.
A sequence of DNA, similar to the sequence for an active gene, but that does not produce a protein. It could be a duplicated copy of a gene that contains a mutation that inactivates the copy.
Stretch of DNA related in sequence to a funtional gene; it is however inactive as a result of the changes it has accumulated during evolution.
A functionless segment of DNA exhibiting sequence homology to a functional gene. A nonfunctional member of a gene family.
A gene that closely resembles a known functional gene at another locus, yet has become nonfunctional, due to an accumulation of mutational defects that prevent normal transcription or translation.
A DNA segment that is homologous to a functional gene but contains a nucleotide change that prevents its expression.
Genes that are similar in DNA sequence to coding genes but that have been altered so that they cannot be transcribed or translated.
a DNA sequence that has similar structure to an expressed gene and is presumed to have once been functional but has acquired mutations that render it nonfunctional
a DNA sequence that resembles a gene but appears to be nonfunctional
a gene copy that does not produce a functional, full-length protein
a non-coding section of DNA that resembles a functional gene, in that it has sequences homologous (similar) with those of functional genes, but it lacks the signals which allow it to be expressed
a non-functional copy of a gene, usually one whose nucleotide sequence has changed so that its biological information has become unreadable (see p
a nucleotide sequence that is part
a piece of noncoding DNA very similar in sequence to a
a sequence of bases in the DNA that clearly resembles the sequence of a known gene, but differs from it in some crucial respect and has no function
a stretch of DNA that codes for a protein, but it lacks one of the control regions, and therefore it can't be turned on to actually produce protein
A copy of a gene that usually lacks introns and other essential DNA sequences necessary for function; pseudogenes, though genetically similar to the original functional gene, are not expressed and often contain numerous mutations Related Terms: deletion ; duplication ; gene conversion ; unequal crossing over
a gene which transcribes a non-functional peptide due to mutation(s). For example, a nuclear pseudogene of mtDNA is a copy of non-functional mtDNA gene incorpotated in the nuclear genome - a possible source of bias when mtDNA analysis is based on PCR with total genomic DNA as a template.
A sequence of DNA similar to a gene but nonfunctional; probably the remnant of a once-functional gene that accumulated mutations.
a DNA sequence that bears strong similarity to a functioning gene, but whose protein product is not very likely to be biologically active. Gene families often contain pseudogene members that may have arisen from a f unctional gene during evolution.
a gene that has been inactivated in the past by an insertion or deletion of DNA. Return to text.
A gene that is very similar to a known gene at a different locus but is made nonfunctional by additions or deletions to its structure that prevent normal transcription or translation.
A DNA sequence similar to that of an active gene. Pseudogenes have collected mutations that render them inactive.
A gene copy created by a gene duplication event that is no longer functional due to a disabling mutation.
An inactive gene derived from an ancestral active gene.
Pseudogenes are defunct relatives of known genes that have lost their protein-coding ability or are otherwise no longer expressed in the cell.Vanin, E. F. (1985). "Processed pseudogenes: characteristics and evolution."
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