The field of science that studies how genetic inheritance affects the way that the body responds to medications.
The study of individual genetic differences in response to drug therapy.
Term given to the use of genetic and genomic information to understand the response of individual patients and patient populations to drugs.
the study of how an individual's genetic inheritance (genome) affects the body's response to drugs and the use of genetic testing in conjunction with drug therapy
The evaluation of individual genomic variation in relation to the delivery and effectiveness of drugs. Knowledge of individual genotype and hence phenotype makes it possible to customize drugs and drug delivery methods for specific subgroups.
branch of pharmaceutics which aims to tailor medicines to an individualâ€™s genetic makeup
the influence of genetic make-up on response to drugs
A new technology that seeks to correlate drug response to a person's genetic profile. Most drugs work for some people, don't work for others and can cause severe side effects in a few. Pharmacogenomics identifies genes that cause these varying responses in order to develop tests for determining who will benefit from a drug and who will not.
The use of genome information to predict individual responses to drug therapies (e.g. adverse drug reactions).
Pharmacogenomics is the analysis of the effect of genomics—in particular, genetic variation (polymorphisms)—on drug response. This practice can potentially help clinicians administer more tailored treatment. The term pharmacogenetics is often used to refer specifically to tests that predict drug response; however, the terms pharmacogenetics and pharmacogenomics are often used interchangeably. [CHI Predictive Pharmacogenomics report
study of the effects of individual genetic variations on drug response; aimed at the prescription or development of drugs that maximize benefit and minimize side effects in individuals
Molecular testing that provides information on how a patient will react to a drug, based on their underlying biological variations.
where drug companies are collecting genetic information to make medicines tailored to specific genes. (Church et al., 2002)
The study of how variations in the human genome affects the response to medications. This will drugs to be tailor-made for individuals and adapted to each persons own genetic makeup.
Developing field of scientific inquiry that examines how drugs interact with genetic differences between individuals.
A method that employs genetic and genomic information to predict the response of individual patients and patient populations to drugs.
The application of genomic information to drugs in clinical development/on the market.
The determination and analysis of the genome (DNA) and its products (RNAs) as they relate to drug response.
study of the interaction of individual genetic varations on the response of drug treatments
The application of genome science (genomics) to the study of human variability in drug response.
The study of the effect of an individual's genotype on the body's potential response to medications.
Pharmacogenomics is the use of genetic information to predict the safety, toxicity and/or efficacy of drugs in individual patients or groups of patients.
makes use of the knowledge of the DNA sequences for the development of new drugs.
A biotechnological science that combines the techniques of medicine, pharmacology and genomics and is concerned with developing drug therapies to compensate for genetic differences in patients which cause varied responses to a single therapeutic regimen.
The blending of genomics with the study of drugs (pharmacology) to determine how variations in the human genome affect a person's response to medications.
The study of differential gene expression applied to drug discovery and optimisation.
An important area of life science research which promises to facilitate the drug development process in the future. Compares the genetic information of an individual to the average human genome to discover genetic varations, and to predict the response of individual patients and patient populations to specific drugs.
This term is not distinctly differentiated from pharmacogenetics, but implies the examination of whole genomes or substantial numbers of genes in order, for example, to identify putative targets for medicines or to identify large-scale differences in the patterns of gene expression in response to chemical compounds.
The study of the pharmacological response to a drug by a population based on the genetic variation of that population. It has long been known that different individuals in a population respond to the same drug differently, and that these variations are due to variations in the molecular receptors being affected by the drug, or to differences in metabolic enzymes that clear the drug. Pharmacogenomics is the science of studying these variations at the molecular level. Applications of pharmacogenomics include reducing side effects, customizing drugs, improvement of clinical trials, and the rescue of some drugs that have been banned due to severe side effects in a small percentage of the eligible population.
examination of the genetic basis for variation in response to therapeutics by different individuals.
Pharmacogenomics is the testing of individuals to predict their genetic pre-disposition to drug response. The field of study looks at how genetic variations among the population affect drug response. It involves the analysis of genomic data to develop a screening process for more efficient clinical trials and molecular diagnostic tests used to determine individualized drug responses. It also looks at how a new targeted drug therapy could be developed using genomic data and analysis.
The study of interaction of an individualÃ•s genetic makeup and response to a drug.
Refers to the study of how an individual's genetic inheritance affects the body's response to drugs. The term comes from the words pharmacology and genomics and is thus the intersection of pharmaceuticals and genetics. This science holds the promise that drugs might one day be tailor-made for individuals and adapted to each person's own genetic makeup. Environment, diet, age, lifestyle, and state of health all can influence a person's response to medicines, but understanding an individual's genetic makeup is thought to be the key to creating personalized drugs with greater efficacy and safety. Pharmacogenomics combines traditional pharmaceutical sciences such as biochemistry with annotated knowledge of genes, proteins, and single nucleotide polymorphisms.
The science of understanding the correlation between an individual patient's genetic make-up (genotype) and their response to drug treatment. Some drugs work well in some patient populations and not as well in others. Studying the genetic basis of patient response to therapeutics allows drug developers to more effectively design therapeutic treatments. Source : Human Genome Project Information
Study of genetic variation underlying differential response to drugs.
Pharmacogenomics is the branch of pharmaceutics which deals with the influence of genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with a drug's efficacy or toxicity. By doing so, pharmacogenomics aims to develop rational means to optimise drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Such approaches promise the advent of "personalised medicine", in which drugs and drug combinations are optimised for each individual's unique genetic makeup.