(kin net´ oh core) [Gr. kinetos: moving + khorein: to move] • Specialized structure on a centromere to which microtubules attach.
Specialized structure that forms at the centromere and to which the microtubules attach during mitosis and meiosis.
the point at the centromere where the mitotic spindle attaches
A pair of structures adjacent to the chromosomal centromere to which spindle microtubules attach.
a region of DNA that has remained undivided during prophase of mitosis; binds to the spindle fibers that eventually pull apart the sister chromatids.
Complex structure formed from proteins on a mitotic chromosome to which microtubules attach and which plays an active part in the movement of chromosomes to the pole. The kinetochore forms on the part of the chromosome known as the centromere.
A Spindle attachment. A localized region in each chromosome to which the `spindle fiber' appears to be attached and which seems to determine movement of the chromosomes during mitosis and meiosis.
a structure forming at the centromere during mitosis for binding microtubules; a platelike structure necessary for chromosomal movement during mitosis; it develops on the centromere and links the chromosomes to the mitotic spindle
The chromosomal attachment point for the spindle fibers located within the centromeres.
a specialized condensed region of each chromosome that appears during mitosis where the chromatids are held together to form an X shape; "the centromere is difficult to sequence"
Structure forming at centromere during mitosis for binding microtubules, a complex of proteins (11 in budding yeast) that forms at the centromere and helps to separate the sister chromatids.
A disc of proteins located on the centromere, specialized to interact with the spindle fibers during mitosis.
The point of attachment for the spindle fibers onthe centromere of chromosomes during mitosis or meiosis.
the chromosomal point of attachment for spindle fibers during mitosis and meiosis; located on the centromere
specialized region in the centromeres of chromosomes that attach chromosomes to polar fibers via kinetochore fibers.
The part of the centromere to which spindle microtubules attach.
A three-layer protein structure located at or near the centromere of each mitotic chromosome from which microtubules (kinetochore fibers) extend toward the spindle poles of the cell; plays an active role in movement of chromosomes toward the poles during anaphase.
A protein complex which associates with the centromere of a chromosome to bind the chromosome to the mitotic spindle. The kinetochore plays an active role in associating with microtubules, and perhaps also in driving assembly or disassembly of the mitotic spindle. There are two regions of the kinetochore, an inner region which is associated with centromere DNA and an outer region which interacts with microtubules. C. elegans is a holocentric organism, so that instead of having a single localized centromeric region on the chromosome (monocentric), it assembles diffuse kinetochores along the entire poleward face of each sister chromatid, which facilitates a high rate of chromosomal rearrangements and translocations ( Coghlan, 2005). See Holocentric See Monocentric
The kinetochore is the protein structure in eukaryotes which assembles on the centromere and links the chromosome to microtubule polymers from the mitotic spindle during mitosis and meiosis. The kinetochore contains two regions: an inner kinetochore, which is tightly associated with the centromere DNA; and an outer kinetochore, which interacts with microtubules. "Monocentric" organisms, including vertebrates, fungi, and most plants, have a single centromeric region on each chromosome which assembles one kinetochore.