A hereditary, progressive disease, transmitted as an autosomal recessive trait. In addition to ataxia, it is associated with vascular lesions of the skin and eye, frequent respiratory infections, abnormal movements of the eyes and immune system disorders.
Rare genetic disease in which there is abnormal sensitivity to X-rays, deficient repair of X-ray damage to DNA, immune deficiency, and extremely high rate of cancers of white blood cells.
Hereditary disorder characterized by problems with muscle coordination, immunodeficiency, inadequate DNA repair, and an increased risk of developing cancer.
A rare genetic disorder in which cells in the body don't have the ability to repair damage to DNA caused by ionizing radiation (like X-rays).
Ataxia-telangiectasia (AT) (Boder-Sedgwick syndrome or Louis-Bar syndrome) is a primary immunodeficiency disorder that occurs in an estimated incidence of 1 in 40,000 to 1 in 300,000 births (Lederman, 2000).