a persistent change in a single gene.

a heritable alteration in the genetic material.

Mutation (point or larger change) that results from changes within the structure of a gene.

See mutation.

a mutation due to an intramolecular reorganization of a gene

a change in a hereditary factor that is based on a structural change of the respective gene

a change in nucleotide sequence of a gene

a change in one or more of the bases that make up a gene

a change in one to several bases in the nucleotide sequence of DNA, which can result in a change in the protein synthesized

a change in the gene code

a chemical change in the gene itself

an alteration in the DNA (deoxyribonucleic acid) nucleotide sequence of an allele

an alteration in the DNA nucleotide sequence , producing an alternate sequence, termed an allele

a permanent change in the DNA sequence that makes up a gene

a spontaneous or inherited change in a gene that allows an altered characteristic or disorder to appear

A change in the genetic material. It can include all genetic alterations from single nucleotide substitutions to whole chromosome translocations.

Human genes are made up of four chemicals or nucleotides which are called adenine, cytosine, guanine and thymine. Genetic sequence of a person depends on the order of these four nucleotides. When a mutation occurs, one or a few of these nucleotides are missing or altered in a sequence.

A change in a gene so it does not work in the normal way. Mutations to the BRCA1 or BRCA2 gene put a person at greater risk for developing breast and ovarian cancer than those who do not have the mutation.

a point mutation that results from changes within the structure of a gene.

an abnormality in the sequence of bases of a gene.