Sub-class of lymphocytes. Considered to be responsible for graft-versus-host disease
Type of white blood cells
Also called T-cells. These are specialised cells which respond to stimulation by dendritic cells plus a peptide antigen. They have multiple roles in the immune response including directly attacking abnormal cells and regulating the response of other T cells.
Lymphoid cells concerned with cell-mediated immunity. They originate from lymphoid stem cells that migrate from the bone marrow to the thymus and differentiate under the influence of the thymic hormones. Various subpopulations have been described.
White blood cells produced by the thymus gland in the upper chest. There are many different types of T-cells, all with different jobs in the immune system.
White blood cells that tell the body to attack foreign cells, which could cause infections.
Cells produced in the bone marrow and mature in the thymus that are responsible for the second branch of the immune system called the “cellular immune response.” T-cells can live for months to years.
Relatively long-lived cell which plays a key role in cellular immunity
The T-lymphocytes are differentiated in the thymus, a small organ behind the sternum. The T-lymphocytes carry a protein complex on their cell surface that can recognise and bind antigens. The protein complex only reacts with the antigen specific to it, like to a key that only fits a specific lock. This results in activation of the T-lymphocytes. A distinction is made between cytotoxic T-lymphocytes that can bind and dissolve cells recognised as foreign, i.e. antigen-bearing cells, and the T-helper lymphocytes. By means of the production of various growth factors, these enable the differentiation between B-lymphocytes and cells producing antibodies.