a condition in which a genetic male or female has the gender identity of the opposite sex. (391)

also known as gender dysphoria; occurs when gender identity does not match biological gender.

Attempts by the individual to assume the physical characteristics of the opposite sex: the symptom complex of gender dysphoria.

Severe gender dysphoria, coupled with a persistent desire for the physical characteristics and social roles that connote the opposite biological sex.

condition in which a person assumes the identity and permanently acts the part of the gender opposite to his or her biological sex

The desire to live as a member of a different gender than one's anatomical or genetic gender. Some transsexuals choose to reassign their physical sex through surgery and hormone therapy.

Transsexualism is a condition in which a transsexual person self-identifies as a member of the gender opposite to the one assigned to them at birth. Transsexualism is considered a taboo subject in many parts of the world. The justifications for negative beliefs about transsexualism may be perceived as being supported by religious beliefs or cultural norms.