Compare? The lowest level of a stressor that causes statistically and biologically significant differences in test samples as compared to other samples subjected to no stressor.
LOAELs have been classified into "less serious" or "serious" effects. In dose-response experiments, the lowest exposure level at which there are statistically or biologically significant increases in the frequency or severity of adverse effects between the exposed population and its appropriate control.
Lowest amount or concentration of an agent, found by experiment or observation, that causes an adverse alteration of morphology, functional capacity, growth, development or life span in an organism, system or (sub)population.
The LOAEL is the lowest dose at which an adverse health effect is seen in a particular study. The LOAEL is often used to derive MRLs and RfDs.
The lowest tested dose of a substance that has been reported to cause harmful (adverse) health effects in persons or animals.
The lowest dose of a chemical that produced an adverse-effect when it was administered to animals in a toxicity study.