MetaGlossary.com: Lowest Observed Adverse Effect Level

Definitions for "Lowest Observed Adverse Effect Level" Add To Word List

Keywords: Loael, Dose, Adverse, Rfds, Stressor

Related Terms: Hazard, Toxicity, Toxicologist, Threshold, Risk Assessment, Rfd, Endpoint , Adverse Effect, Acute Effect, Chronic Toxicity, Lethal Concentration 50, Ecological Risk Assessment, Dose-Response, Dose-Response Assessment, Exposure Assessment, Minimal Risk Level, Acute Toxicity, Slope Factor, Stochastic Effect, Dose-Response Relationship, Noec, Risk Characterization, Ec50, Loec, Hazard Assessment, Adverse Drug Reaction, Noel, Emeg, Acceptable Daily Intake, Baseline Risk Assessment, Uncertainty Factor, Hazard Identification, Critical Load, Environmental Monitoring, Comparison Value, Noael, Reference Dose, Health Risk Assessment, Biological Monitoring, Dose Response, Ed50, Maximum Tolerated Dose, Environmental Risk, No Observed Adverse Effect Level, Target Organ, Rmeg, Adverse Effects, Loael, Reference Concentration

Submit a better definition with this meaning

Compare? The lowest level of a stressor that causes statistically and biologically significant differences in test samples as compared to other samples subjected to no stressor.

http://iaspub.epa.gov/trs/trs_proc_qry.alphabet?p_term_nm=L&p_reg_auth_id=1...

Helpful?

LOAELs have been classified into "less serious" or "serious" effects. In dose-response experiments, the lowest exposure level at which there are statistically or biologically significant increases in the frequency or severity of adverse effects between the exposed population and its appropriate control.

http://www.atsdr.cdc.gov/HAC/PHA/cenex/csm_toc.html

Helpful?

Lowest amount or concentration of an agent, found by experiment or observation, that causes an adverse alteration of morphology, functional capacity, growth, development or life span in an organism, system or (sub)population.

http://www.fsra.net/glossary.html

Helpful?

The LOAEL is the lowest dose at which an adverse health effect is seen in a particular study. The LOAEL is often used to derive MRLs and RfDs.

http://www.atsdr.cdc.gov/hac/pha/bertrand/ber_p4.html

Helpful?

The lowest tested dose of a substance that has been reported to cause harmful (adverse) health effects in persons or animals.

http://www.atsdr.cdc.gov/HAC/PHA/ridgefield/rpw_toc.html

Helpful?

The lowest dose of a chemical that produced an adverse-effect when it was administered to animals in a toxicity study.

http://www.atsdr.cdc.gov/HAC/PHA/castle/cas_p2.html

Helpful?

Privacy Statement | Terms of Use