DNA or RNA molecule which has been artificially manipulated to allow binding with other molecules and viruses.
A small piece of DNA or RNA engineered to bind to a specific protein. Aptamers can be used in microarray experiments to capture a specific protein from a mixture. Aptamers can be conjugated to other molecules like fluorophores, to allow high-sensitivity detection of proteins, even in very small amounts. See also Fluorophores, Microarray.
a single chain of DNA or RNA that selectively binds to a protein
a single strand of oligonucleotide that binds with specificity to a particular target, such as VEGF
short strands of DNA or RNA that are designed to bind to certain target molecules.
A single-stranded, short sequence of nucleic acid.
Aptamers first discribed by Mostafa R.,et al. are oligonucleic acid or peptide molecules that bind a specific target molecule. Aptamers are usually created by selecting them from a large random sequence pool, but natural aptamers also exist in riboswitches. Aptamers can be used for both basic research and clinical purposes as macromolecular drugs.