Pain of mind on account of something in the past; mental suffering arising from any cause, as misfortune, loss of friends, misconduct of one's self or others, etc.; sorrow; sadness.

Cause of sorrow or pain; that which afficts or distresses; trial; grievance.

Emotional response experienced in the early phases of bereavement. (618)

intense emotional suffering caused by loss, disaster, misfortune, and so on; acute sorrow; deep sadness.