An antibody made locally in mucosal-associated lymphatic tissue. It is produced early in the immune response to a pathogen, before IgG.
antibodies IgMs are the first circulating antibodies to appear in response to an antigen. However, their concentration in the blood declines rapidly. This is diagnostically useful, because the presence of IgM usually indicates a current infection by the pathogen causing its formation. IgM consists of five Y-shaped monomers arranged in a pentamer structure. The numerous antigen-binding sites make it very effective in agglutinating antigens. IgM is too large to cross the placenta and hence does not confer maternal immunity.
one of the five major classes of immunoglobulins; involved in fighting blood infections and in triggering production of immunoglobulin G
A form of IG produced in most immune responses during the early period of a reaction.
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