Collagen sheets obtained from human organ donors. Placing this collagen under the skin replenishes the missing deeper layers of skin, thereby elevating depressed scars or skin wrinkles. It can also be placed in the lips to make them appear larger. The material can last more than 2 years without any visible loss of the collagen -- but there is no guarantee as to how long the correction will last. The edges of the sheet can felt but not usually seen for 4 to 6 weeks. After that, the edges cannot be felt or seen. Alloderm is not subject to transplant rejection or common infections. It is processed according to U.S. Food and Drug Administration and American Association of Tissue Banks regulations.